Whether you are evaluating the effectiveness of a drug, a medical device, a behavioral intervention, a community mobilization, or even a new law, this is the book for you. Written in plain language, it simplifies the process of designing interventions, analyzing the data, and publishing the results. Because the choice of research design depends on the nature of the intervention, the book covers randomized and nonrandomized designs, prospective and retrospective studies, planned clinical trials and observational studies. In addition to reviewing standard statistical analysis, the book has easy-to-follow explanations of cutting edge techniques for evaluating interventions, including propensity score analysis, instrumental variable analysis, interrupted time series analysis and sensitivity analysis. All techniques are illustrated with up-to-date examples from medical and public health literature. This will be essential reading for a wide range of healthcare professionals involved in research as well as those more specifically interested in public health issues and epidemiology.
The most critical time when changing life style is the first month. Starting on the right path will help ensure that your venture can blossom into a long term commitment. This book will lay the road map for this first month. It is very likely that your mother has told you most of the tips included, but still it is written in a way that you can use it as a mirror to reflect on yourself and learn more about your plan. This book is only one of the series "Positive Living" that I developed to help you improve your quality of life. I invest in positive and I hope you let "positive" flow into your life. You can master the skill of integrating "Positive" in your life, but you have to be diligent about making it a daily habit. The content of these books are timeless, clear, and can be passed on from generation to generation and still continue to be valid and relative. Every household should have this book; it is your first aid when you are trying to adapt a positive life style.
This manual is intended to guide the coordinated implementation of regular, systematic large-scale interventions that provide anthelminthic drug treatment as a core component of the joint and synergic control of helminthic diseases such as lymphatic filariasis onchocerciasis schistosomiasis and soil-transmitted helminthiasis. The manual focuses mainly on antihelminthic treatment, but other drugs used to eliminate other agents can be potentially associated to those mentioned in the manual; as a reference trachoma control through the SAFE strategy combining drug treatment with hygiene and environmental management can be associated to helminth control interventions to boost the overall health of affected communities. The greatest challenge is to extend regular anthelminthic drug coverage as a public health intervention to reach all individuals at risk of the morbidity caused by helminthic infections. Preventive chemotherapy should therefore begin early in life and every opportunity should be taken to reach at-risk populations. This manual advocates much greater coordination among disease control interventions. Because such large numbers of people are affected and are often difficult to reach, it also stresses the need to make the best use of all existing drug distribution channels to deliver anthelminthic drugs and aims at encouraging program managers to find other innovative means of reaching those in need in a sustainable manner.
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